Massari L et al. Biophysical stimulation of bone and cartilage: state of the art and future perspectives. Int Orthop. 2019 Mar;43(3):539-551.


Iwasa K et al. Pulsed Electromagnetic Fields and Tissue Engineering of the Joints. Tissue Eng. 2018;24(2):144-154.


Massari L et al. Focus Group Ortopedia. Impiego clinico della stimolazione elettrica in ortopedia e traumatologia. The use of electrical stimulation in traumatology and orthopaedic practice. Giornale Italiano di Ortopedia e Traumatologia. 2017;43:105-106.

Cadossi R et al. Physical Dynamics: The Base for the Development of Biophysical Treatments. In: Marko Markov, ed. Dosimetry in Bioelectromagnetics. CRC Press 2017;(4):87-100.

Collarile M et al. Biophysical stimulation improves clinical results of matrix-assisted autologous chondrocyte implantation in the treatment of chondral lesions of the knee. Knee Surg Sports Traumatol Arthrosc. 2017 Apr;26(4):1223-1229.


Cadossi R et al.Physical Regulation in Cartilage and Bone Repair. In: Marko S. Markov, ed. Electromagnetic Fields in Biology and Medicine. CRC Press. 2015;(16):253-372.

Osti L et al. Application of pulsed electromagnetic fields after microfractures to the knee: a mid-term study. Int Orthop. 2015 Jul;39(7):1289-1294.

Osti L et al. Pulsed electromagnetic fields after rotator cuff repair: a randomized, controlled study. Orthopedics. 2015 Mar;38(3):e223-228.


Adravanti P et al. Effect of pulsed electromagnetic field therapy in patients undergoing total knee arthroplasty: a randomised controlled trial. Int Orthop. Int Orthop. 2014 Feb;38(2):397-403.

Cadossi M et al. Bone Marrow–derived Cells and Biophysical Stimulation for Talar Osteochondral Lesions: A Randomized Controlled Study. Foot Ankle Int. 2014 Oct;35(10):981-987.


Fini M, et al. Functional Tissue Engineering in Articular Cartilage Repair: Is There a Role for Electromagnetic Biophysical Stimulation? Tissue Eng Part B Rev. 2013 Aug;19(4):353-367.

Vincenzi F et al. Pulsed Electromagnetic Fields Increased the Anti-inflammatory Effect of A2A and A3 Adenosine Receptors in Human T/C-28a2 Chondrocytes and hFOB 1.19 Osteoblasts. PLoS One. 2013 May;8(5):e65561.


Ongaro A et al. Electromagnetic fields (EMFs) and adenosine receptors modulate prostaglandin E(2) and cytokine release in human osteoarthritic synovial fibroblasts. J Cell Physiol. 2012 Jun;227(6):2461-2469.

Moretti B et al. I-ONE therapy in patients undergoing total knee arthroplasty: a prospective, randomized and controlled study. BMC Musculoskelet Disord. 2012 Jun 6;13(1):88.


Ongaro A et al. Chondroprotective effects of pulsed electromagnetic fields on human cartilage explants. Bioelectromagnetics. 2011 Oct;32(7):543-551.


De Mattei M et al. Adenosine analogs and electromagnetic fields inhibit prostaglandin E(2) release in bovine synovial fibroblasts. Osteoarthritis Cartilage. 2009 Feb;17(2):252-262


Varani K et al. Characterization of adenosine receptors in bovine chondrocytes and fibroblastlike synoviocytes exposed to low frequency low energy pulsed electromagnetic fields. Osteoarthritis Cartilage. 2008;16(3):292-304.

Fini M et al. Effect of pulsed electromagnetic field stimulation on knee cartilage, subchondral and epyphiseal trabecular bone of aged Dunkin Hartley guinea pigs. Biomed Pharmacother. 2008 Dec;62(10):709-715.

Benazzo F et al. Effects of biophysical stimulation in patients undergoing arthroscopic reconstruction of anterior cruciate ligament: prospective, randomized and double blind study. Knee Surg Sports Traumatol Arthrosc. 2008 Jun;16(6):595-601.

Benazzo F et al. Cartilage repair with osteochondral autografts in sheep: effect of biophysical stimulation with pulsed electromagnetic fields.J Orthop Res. 2008 May;26(5):631-642.


Eriksson E. Can pulsed electromagnetic fields protect joint cartilage? Knee Surg Sports Traumatol Arthrosc. 2007 Jul;15(7):829.

Zorzi C et al. Effects of pulsed electromagnetic fields on patients’ recovery after arthroscopic surgery: prospective, randomized and double-blind study. Knee Surg Sports Traumatol Arthrosc. 2007;15(7):830-834.

Massari L et al. CRES Study Group. Effects of electrical physical stimuli on articular cartilage. J Bone Joint Surg Am. 2007;89 Suppl3:152-61. Review.

De Mattei M et al. Proteoglycan synthesis in bovine articular cartilage explants exposed to different low-frequency low-energy pulsed electromagnetic fields. Osteoarthritis Cartilage. 2007;15(2):163-168.


Fini M et al. Pulsed electromagnetic fields reduce knee osteoarthritic lesion progression in the aged Dunkin Hartley guinea pig. J Orthop Res. 2005;23(4):899-908.

Fini M et al. Effects of pulsed electromagnetic fields on articular hyaline cartilage: review of experimental and clinical studies. Biomed Pharmacother. 2005;59(7):388-394.

De Mattei M et al. Effects of physical stimulation with electromagnetic field and insulin growth factor-I treatment on proteoglycan synthesis of bovine articular cartilage. Osteoarthritis Cartilage. 2004;12(10):793-800.


De Mattei M et al. Effects of electromagnetic fields on proteoglycan metabolism of bovine articular cartilage explants. Connect Tissue Res. 2003;44(3-4):154-159.


Varani K et al. Effect of low frequency electromagnetic fields on A2A adenosine receptors in human neutrophils. Br J Pharmacol. 2002;136(1):57-66.


De Mattei M et al. Effects of pulsed electromagnetic fields on human articular chondrocyte proliferation. Connect Tissue Res. 2001;42(4):269-279.


Pezzetti F et al. Effects of pulsed electromagnetic fields on human chondrocytes: an in vitro study. Calcif Tissue Int. 1999;65(5):396-401.

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