Here following a wide selection of the scientific papers on electrochemotherapy published in peer reviewed interantional journals.
Last updated 22 November 2018.
At the end of this page you will find the booklet "ELECTROCHEMOTHERAPY: a combined treatment" that contains the same bibliographic entries quoted in this page ordered by pathology and  and the most representative guidelines that mention electrochemotherapy.


Esmaeili N et al. Electrochemotherapy: A Review of Current Status, Alternative IGP Approaches, and Future Perspectives. J Healthc Eng 2019, 2019:2784516.

Kristiansson S et al. Long-term follow-up in patients treated with electrochemotherapy for non-melanoma skin cancer in the head and neck area. Acta Otolaryngol. 2019, Feb 8:1-6 [Epub ahead of print].

Pichi B et al. Electrochemotherapy - A locoregional therapy with well-established palliative effect in patient with large recurrent lesion of head and neck. Journal of Cranio-Maxillo-Facial Surgery 2019, (47):41-46.

Cornelis FH et al. Multimodal image-guided electrochemotherapy of unresectable liver metastasis from renal cell cancer. Diagn Interv Imaging. 2019 [Epub ahead of print].

Granata V et al. Diffusion kurtosis imaging and conventional diffusion weighted imaging to assess electrochemotherapy response in locally advanced pancreatic cancer. Radiol Oncol. 2019, Jan 19;53(1):15-24.

Campana LG et al. Electrochemotherapy - Emerging applications technical advances, new indications, combined approaches, and multi-institutional collaboration. Eur J Surg Oncol. 2019 Feb;45(2):92-102.

Plaschke CC et al. The DAHANCA 32 study: Electrochemotherapy for recurrent mucosal head and neck cancer. Head Neck. 2019 Feb;41(2):329-339.


Goggins CA et al. The use of electrochemotherapy in combination with immunotherapy in the treatment of metastatic melanoma: a focused review. Int J Dermatol 2018 [Epub ahead of print].

Probst U et al. Electrochemotherapy as a New Modality in Interventional Oncology: A Review. Technol Cancer Res Treat 2018, 17:1-12.

Seyed Jafari SM et al. Application of electrochemotherapy in the management of primary and metastatic cutaneous malignant tumours: a systematic review and meta-analysis. Eur J Dermatol 2018, 28(3):287-313.

De Virgilio A et al. Electrochemotherapy in head and neck cancer: A review of an emerging cancer treatment. Oncol Lett 2018, 16(3):3415-3423.

Pichi B et al. Electrochemotherapy: a well-accepted palliative treatment by patients with head and neck tumours. Acta Otorhinolaryngol Ital 2018, 38(3):181-187.

Gargiulo M et al. Long term effectiveness of electrochemotherapy for the treatment of lower lip squamous cell carcinoma. J Craniomaxillofac Surg 2018, 46(11):1968-1974.

Matthiessen LW et al. Electrochemotherapy for Breast Cancer-Results From the INSPECT Database. Clin Breast Cancer. 2018 Oct;18(5):e909-e917.

Tarantino L et al. Electrochemotherapy of cholangiocellular carcinoma at hepatic hilum: A feasibility study. Eur J Surg Oncol 2018, 44(10):1603-1609

Boc N et al. Ultrasonographic changes in the liver tumors as indicators of adequate tumor coverage with electric field for effective electrochemotherapy. Radiol Oncol. 2018 Oct 18;52(4):383-391.

Padilla-España L et al. Electrochemotherapy With Intravenous Bleomycin in the Treatment of Unresectable Merkel Cell Carcinoma. Actas Dermosifiliogr 2018 Aug 17. pii: S0001-7310(18)30364-8.

Ascierto PA et al. Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy). J Transl Med 2018, 16(1):207.

Wichtowski M et al. Electrochemotherapy in the treatment of melanoma. Contemp Oncol (Pozn). 2018;22(1):8-13.

Perrone AM et al. Electrochemotherapy pre-treatment in primary squamous vulvar cancer. Our preliminary experience. J Surg Oncol. 2018. [epub ahead of print].

Rotunno R et al. Electrochemotherapy of unresectable cutaneous tumors with reduced dosages of intravenous bleomycin: analysis of 57 patients from the InspECT (International network for sharing practices of ElectroChemoTherapy) registry. J Eur Acad Dermatol Venereol. 2018 Jul;32(7):1147-1154.

Egeland C et al. Endoscopic electrochemotherapy for esophageal cancer: a phase I clinical study. Endosc Int Open. 2018;6(6):E727-E734.

Pasquali P et al. Successful Treatment of a Keratoacanthoma with Electrochemotherapy: A Case Report. Dermatol Ther (Heidelb). 2018;8(1):143-146.

Cindrič H et al. Electrochemotherapy of Spinal Metastases Using Transpedicular Approach-A Numerical Feasibility Study. Technol Cancer Res Treat. 2018 Jan;17:1533034618770253.

Gehl J et al. Updated standard operating procedures for electrochemotherapy of cutaneous tumours and skin metastases. Acta Oncol. 2018;25:1‐9.

Montuori M et al. Electrochemotherapy for basocellular and squamocellular head and neck cancer: preliminary experience in day surgery unit. G Ital Dermatol Venereol. 2018;153(1):19-25.

Al‐Hadithy N et al. Patient reported outcomes in prospective cohort study of Electrochemotherapy. Int J Surg. 2018;52:110‐119.

Djokic M et al. Electrochemotherapy as treatment option for hepatocellular carcinoma, a prospective pilot study. Eur J Surg Oncol. 2018 May;44(5):651-657.


Campanacci L et al. Electrochemotherapy in the treatment of bone metastases. GIOT. 2017;43:24-28.

Wichtowski M et al. Electrochemotherapy in Breast Cancer - Discussion of the Method and Literature Review. Breast Care (Basel). 2017;12(6):409-41.

Lenzi R et al. The controversial role of electrochemotherapy in head and neck cancer: a systematic review of the literature. Eur Arch Otorhinolaryngol. 2017;274(6):2389-2394.

Testori A et al. Diagnosis and treatment of in-transit melanoma metastases.Eur J Surg Oncol. 2017;43(3):544-560.

Aguado-Romeo MJ et al. Electrochemotherapy for the Treatment of Unresectable Locoregionally Advanced Cutaneous Melanoma: A Systematic Review. Actas Dermosifiliogr. 2017;108(2):91-97.

Guida M et al. Image Gallery: A case of cutaneous giant angiosarcoma treated successfully with electrochemotherapy. Br J Dermatol. 2017;177(2):e27.

Bourke M et al. Effective treatment of intractable cutaneous metastases of breast cancer with electrochemotherapy: a useful contributor to cutaneous disease control. Breast Cancer Res Treat. 2017;163(2):403-405.

Campana LG et al. Treatment of cutaneous metastases of breast cancer with electrochemotherapy: what is the magnitude of clinical benefit? Breast Cancer Res Treat. 2017;163(2):399-401.

Wichtowski M et al. Electrochemotherapy in the treatment of massive, multisite breast cancer metastasis to the skin and subcutaneous tissue: A case report. Breast Care (Basel). 2017; 11(5):353-355.

Bourke MG et al. Effective treatment of intractable cutaneous metastases of breast cancer with electrochemotherapy: Ten-year audit of single centre experience. Breast Cancer Res Treat. 2017;161(2):289-297.

Vitfell-Rasmussen J et al. Tumor reduction and symptom relief after electrochemotherapy in a patient with aggressive fibromatosis - a case report. Acta Oncol. 201;16:1-4.

Plaschke CC et al. European Research on Electrochemotherapy in Head and Neck Cancer (EURECA) project: results from the treatment of mucosal cancers. Eur J Cancer. 2017;87:172-181.

Gargiulo M et al. A relapsed lower lip squamous cell carcinoma treated with curative electrochemotherapy in elderly patient. Minerva Stomatol. 2017;67(1):32-33.

Gasljevic G et al. Histopathological findings in colorectal liver metastases after electrochemotherapy. PLoS One. 2017;12(7):e0180709.

Klein N et al. Treatment of lymph node metastases from gastric cancer with a combination of Irreversible Electroporation and Electrochemotherapy: a case report. Clin Case Rep. 2017;5(8):1389-1394.

Mofid B et al. Effective Treatment of Cervical Lymph Node Metastasis of Breast Cancer by Low Voltage High-Frequency Electrochemotherapy. Acta Med Iran. 2017;55(4):268-271.

Karaca B et al. Electrochemotherapy with anti-PD-1 treatment induced durable complete response in heavily pretreated metastatic melanoma patient. Anticancer Drugs. 2017 Dec 21. [Epub ahead of print]

Klein N et al. Prostate cancer infiltrating the bladder sphincter successfully treated with Electrochemotherapy: a case report. Clin Case Rep. 2017;5(12):2127-2132.

McMorrow L et al. Bleomycin electrosclerotherapy: new treatment to manage vascular malformations. Br J Oral Maxillofac Surg. 2017;55(9):977-979.

Baltás E et al. Electrochemotherapy for non-melanoma skin cancer in a child with xeroderma pigmentosum. Acta Derm Venereol. 2017;97(8):962-964.

Groselj A et al. Efficiency of electrochemotherapy with reduced bleomycin dose in the treatment of nonmelanoma head and neck skin cancer: Preliminary results. Head & Neck. 2017;1–6.

Spanggaard I et al. Gene therapy for patients with advanced solid tumors: a phase I study using gene electrotransfer to muscle with the integrin inhibitor plasmid AMEP. Acta Oncol. 2017;56(7):909-916.

Granata V et al. Early radiological assessment of locally advanced pancreatic cancer treated with electrochemotherapy.  World J Gastroenterol. 2017 Jul;23(26):4767-4778.

Gasljevic G et al. Histopathological findings in colorectal liver metastases after electrochemotherapy. PLoS One. 2017 Jul;12(7):e0180709.

Grischke EM et al. Electrochemotherapy - supplementary treatment for loco-regional metastasized breast carcinoma administered to concomitant systemic therapy. Radiol Oncol. 2017 Jun;51(3):317-323.

Starita N et al. Effect of electrochemotherapy on human herpesvirus 8 kinetics in classic Kaposi sarcoma. Infect Agent Cancer. 2017 Aug12:35.

Coletti L et al. Safety and feasibility of electrochemotherapy in patients with unresectable colorectal liver metastases: A pilot study. Int J Surg. 2017 May;44:26-32.

Campana LG et al. Basal cell carcinoma: 10-year experience with electrochemotherapy. J Transl Med. 2017 Apr;15(1):122.

Di Monta G et al. Electrochemotherapy efficacy evaluation for treatment of locally advanced stage III cutaneous squamous cell carcinoma: a 22-cases retrospective analysis. J Transl Med. 2017 Jun;15(1):82.

Fava P et al. Treatment of metastatic melanoma: a multidisciplinary approach. G Ital Dermatol Venereol. 2017 Feb;152(3):241-261.

Tarantino L et al. Percutaneous electrochemotherapy in the treatment of portal vein tumor thrombosis at hepatic hilum in patients with hepatocellular carcinoma in cirrhosis: A feasibility study. World J Gastroenterol. 2017;23(5):906-918.

Kunte C et al. Electrochemotherapy in the treatment of metastatic malignant melanoma: A prospective cohort study by InspECT. Br J Dermatol. 2017;176(6):1475-1485.


Testori A et al. Diagnosis and treatment of in-transit melanoma metastases. Eur J Surg Oncol. 2016 Oct 27. pii: S0748-7983(16)30941-6. doi: 10.1016/j.ejso.2016.10.005. fof print]

Ribero S et al. Metastatic sebaceous cell carcinoma, review of the literature and use of electrochemotherapy as possible new treatment modality. Radiol Oncol. 2016 Jul 19;50(3):308-12. doi: 10.1515/raon-2016-0039.

Dolinsek T et al. Electrochemotherapy with bleomycin is effective in BRAF mutated melanoma cells and interacts with BRAF inhibitors. Radiol Oncol. 2016 Jul 19;50(3):274-9. doi: 10.1515/raon-2016-0042.

Zygogianni A et al. Potential Role of Electrochemotherapy as Anticancer Treatment for Cutaneous and Subcutaneous Lesions. Asian Pac J Cancer Prev. 2016;17(8):3753-3757.

Tomassini GM et al. Electrochemotherapy with intravenous bleomycin for advanced non-melanoma skin cancers and for cutaneous and subcutaneous metastases from melanoma. G Ital Dermatol Venereol. 2016 Oct;151(5):499-506.

Campana LG et al. Electrochemotherapy: mechanism of action and clinical results in the locoregional treatment of patients with skin cancers and superficial metastases. Recenti Prog Med. 2016 Aug;107(8):422-433.

Di Gennaro P et al. CD4+FOXP3+ T regulatory cells decrease and CD3+CD8+ T cells recruitment in TILs from melanoma metastases after electrochemotherapy. Clin Exp Metastasis. 2016 Dec;33(8):787-798.

Theurich S et al. Local Tumor Treatment in Combination with Systemic Ipilimumab Immunotherapy Prolongs Overall Survival in Patients with Advanced Malignant Melanoma. Cancer Immunol Res. 2016 Sep 2;4(9):744-54.

Bianchi G et al. Electrochemotherapy in the Treatment of Bone Metastases: A Phase II Trial. World J Surg. 2016 Dec;40(12):3088-3094.

Campana LG et al. Treatment efficacy with electrochemotherapy: A multi-institutional prospective observational study on 376 patients with superficial tumors. Eur J Surg Oncol. 2016 Dec;42(12):1914-1923.

Montuori M et al. Electrochemotherapy for basocellular and squamocellular head and neck cancer: preliminary experience in day surgery unit. G Ital Dermatol Venereol. 2018 Feb;153(1):19-25.

Heppt MV et al. Immune checkpoint blockade with concurrent electrochemotherapy in advanced melanoma: a retrospective multicenter analysis. Cancer Immunol Immunother. 2016 Aug;65(8):951-959.

Bertino G et al. European Research on Electrochemotherapy in Head and Neck Cancer (EURECA) project: Results of the treatment of skin cancer. Eur J Cancer. 2016 Jun 4;63:41-52.

Ribero S et al. Efficacy of electrochemotherapy for eruptive legs keratoacanthomas. Dermatol Ther. 2016 Sep;29(5):345-348.

Guida M et al. Local treatment with electrochemotherapy of superficial angiosarcomas: Efficacy and safety results from a multi-institutional retrospective study. J Surg Oncol. 2016 Aug;114(2):246-53.

Sommerlad M et al. Linear porokeratosis with multiple squamous cell carcinomas successfully treated by electrochemotherapy. Br J Dermatol. Br J Dermatol. 2016 Dec;175(6):1342-1345.

Campana LG et al. Angiosarcoma on Lymphedema (Stewart-Treves Syndrome): A 12-Year Follow-up after Isolated Limb Perfusion, Limb Infusion, and Electrochemotherapy. J Vasc Interv Radiol. 2016 Mar;27(3):444-446.

Pellegrino A et al. Outcomes of Bleomycin-based electrochemotherapy in patients with repeated loco-regional recurrences of vulvar cancer. Acta Oncol. Acta Oncol. 2016 May;55(5):619-624. 


Gasbarrini A et al. Electrochemotherapy to Metastatic Spinal Melanoma: A Novel Treatment of Spinal Metastasis? Spine (Phila Pa 1976). 2015 Dec;40(24):E1340-1346.

Gatti A et al. Curative Electrochemotherapy in Lentigo Maligna Melanoma. Skinmed. 2015 Dec 1;13(6):486-488.

Lido P et al. Cutaneous metastasis of unknown primary presenting as massive and invasive abdominal lesion: an elective approach. An Bras Dermatol. 2015 Dec;90(6):879-882.

Cabula C et al. Electrochemotherapy in the Treatment of Cutaneous Metastases from Breast Cancer: A Multicenter Cohort Analysis. Ann Surg Oncol. 2015 Dec;22 Suppl 3:442-450.

Bonadies A et al. Electrochemotherapy of a Multirecurrent Dermatofibrosarcoma Protuberans of the Orbital Margin: A Case Report. Anticancer Res. 2015 Nov;35(11):6121-6126.

Perrone AM et al. Palliative Electro-Chemotherapy in Elderly Patients With Vulvar Cancer: A Phase II Trial. J Surg Oncol. 2015 Oct;112(5):529-532.

Tschon M et al. Feasibility of Electroporation in Bone and in the Surrounding Clinically Relevant Structures: A Preclinical Investigation. Technol Cancer Res Treat. 2016 Dec;15(6):737-748.

Grau JJ et al. Electrochemotherapy as palliative treatment in patients with thyroid papillary carcinoma. Braz J Otorhinolaryngol. 2016 May-Jun;82(3):285-8.

Rotunno R et al. Electrochemotherapy in non-melanoma head and neck skin cancers: a three centers experience and literature review. G Ital Dermatol Venereol. G Ital Dermatol Venereol. 2016 Dec;151(6):610-618.

Tafuto S et al. Electrochemotherapy as a new approach on pancreatic cancer and on liver metastases. Int J Surg. 2015 Sep;21 Suppl 1:S78-82.

Denzi A et al. Modeling the positioning of single needle electrodes for the treatment of breast cancer in a clinical case. Biomed Eng Online. 2015 Aug 27;14 Suppl 3:S1.

Miklavcic D et al. Electrochemotherapy (ECT) and irreversible electroporation (IRE) – advanced techniques for treating deep-seated tumors based on electroporation. Biomed Eng Online. 2015 Aug 27;14 Suppl 3:I1.

Mali B et al. Electrochemotherapy of colorectal liver metastases – an observational study of its effects on the electrocardiogram. Biomed Eng OnLine. 2015 Aug27;14Suppl3:S5.

Groselj A et al. Coupling treatment planning with navigation system: a new technological approach in treatment of head and neck tumors by electrochemotherapy. BioMedical Engineering OnLine 2015, 14(Suppl 3):S2.

Ricci F et al. Giant neglected squamous cell carcinoma of the skin. Dermatol Ther. 2015 Jul-Aug;28(4):230-234.

Benevento R et al. Angiosarcoma of the breast: a new therapeutic approach? Int J Surg Case Rep. 2015;13:30-2.

Holdsworth R et al. Electrochemotherapy for treatment of Merkel cell carcinoma: A case report. JPRAS. 2015;Vol 6:49-52.

Ruggeri R et al. Electrochemotherapy: a good idea in recurrent basal cell carcinoma treatment. Melanoma Manag. (2015) 2(1), 27–31.

Granata V et al. Electrochemotherapy in locally advanced pancreatic cancer: Preliminary results. Int J Surg. 2015 Jun;18:230-236.

Mozzillo N et al. Assessing a novel immuno-oncology-based combination therapy: Ipilimumab plus electrochemotherapy. Oncoimmunology. 2015 May 22;4(6):e1008842.

Brizio M et al. Complete regression of melanoma skin metastases after electrochemotherapy plus ipilimumab treatment: an unusual clinical presentation. Eur J Dermatol. 2015 May-Jun;25(3):271-272.

Mercantini P et al.Electrochemotherapy Treatment of Cutaneous Metastases from Breast Cancer. Am Surg. 2015 May;81(5):E222-5.

Valpione S et al. Consolidation electrochemotherapy with bleomycin in metastatic melanoma during treatment with dabrafenib. Radiol Oncol 2015; 49(1):71-74.

Mir-Bonafé JM et al. Electrochemotherapy in the treatment of melanoma skin metastases: a report on 31 cases. Actas Dermosifiliogr. 2015 May;106(4):285-291.

Diociaiuti A et al. Electrochemotherapy, a potential new treatment for the management of squamous cell carcinoma in patients with recessive dystrophic epidermolysis bullosa: report of three cases. J Eur Acad Dermatol Venereol. 2016 Jul;30(7):1195-6.

Quaglino P et al. Predicting patients at risk for pain associated with electrochemotherapy. Acta Oncol. 2015 Mar;54(3):298-306.

Girelli R et al. Radiol Oncol 2015;49(2):147-154.

Caracò C et al. Electrochemotherapy in melanoma patients: a single institution experience. Melanoma Manag. 2015;2(2):127–132.

Domanico R et al. Electrochemotherapy in combination with chemoradiotherapy in the treatment of oral carcinomas in advanced stages of disease: efficacy, safety, and clinical outcomes in a small number of selected cases. Drug Des Devel Ther. 2015 Feb 19;9:1185-1191. 

Granata V et al. Feasibility and Safety of Intraoperative Electrochemotherapy in Locally Advanced Pancreatic Tumor: A Preliminary Experience. EJI. 2014;12(3):467-477.

Campana LG et al. Electrochemotherapy in non-melanoma head and neck cancers: a retrospective analysis of the treated cases. Br J Oral Maxillofac Surg. 2014 Dec;52(10):957-64. 

Spratt DE et al. Memorial Sloan-Kettering Cancer Center; Elizabeth A. Gordon Spratt, New York University. Efficacy of Skin-Directed Therapy for Cutaneous Metastases From Advanced Cancer: A Meta-Analysis. J Clin Oncol. 2014 Oct 1;32(28):3144-3155.

Borgognoni L et al. A rare case of anal porocarcinoma treated by electrochemotherapy. Future Oncol. 2014;10(15):2429–2434.

Valpione S et al. Phase I / II study of electrochemotherapy with intravenous bleomycin and variable geometry electric fields for the treatment of deep and large soft tissue tumors. Poster @ ESMO 2014.

Cadossi R et al. Locally enhanced chemotherapy by electroporation: clinical experiences and perspective of use of Electrochemotherapy. Future Oncol. 2014;10(5):877–890.

Campana LG et al. Bleomycin electrochemotherapy in elderly metastatic breast cancer patients: clinical outcome and management considerations. J Cancer Res Clin Oncol. 2014 Sep;140(9):1557-1565. 

Edhemovic I et al. Intraoperative Electrochemotherapy of Colorectal Liver Metastases. J Surg Oncol. 2014 Sep;110(3):320-327.

Queirolo P et al. Electrochemotherapy for the management of melanoma skin metastasis: a review of the literature and possible combinations with immunotherapy. Arch Dermatol Res. 2014 Aug;306(6):521-526.

Gatti A et al. Electrochemotherapy as a novel treatment for primary cutaneous marginal zone B-cell lymphomas. Dermatol Ther. 2014 Jul-Aug;27(4):244-247.

Ricotti F et al. Electrochemotherapy: an effective local treatment of cutaneous and subcutaneous melanoma metastases. Dermatol Ther. 2014 May-Jun;27(3):148-152.

Miklavcic D et al. Electrochemotherapy: from the drawing board into medical practice. Biomed Eng Online. 2014 Mar 12;13(1):29.

Seccia V et al. Electrochemotherapy and Its Controversial Results in Patients with Head and Neck Cancer. Anticancer Res. 2014;34:967-972.

Solari N et al. Electrochemotherapy for the management of cutaneous and subcutaneous metastasis: A series of 39 patients treated with palliative intent. J Surg Oncol. 2014;109(3):270-274.

Carrera C et al. Desmoplastic melanoma on the nose: electrochemotherapy as an alternative treatment to local advanced disease. J Eur Acad Dermatol Venereol. 2014 Apr;28(4):424-432.


Fini M et al. Electrochemotherapy is effective in the treatment of rat bone metastases. Clin Exp Metastasis. 2013 Dec;30(8):1033-1045.

Grischke EM et al. Isolated Loco-Regional Recurrence of Breast Cancer–Established and Innovative Therapy Concepts. Geburtsh Frauenheilk.  2013;73:611–622.

Campana LG et al. Minimally invasive treatment of peristomal metastases from gastric cancer at an ileostomy site by electrochemotherapy. Radiol Oncol. 2013 Oct 8;47(4):370-375.

Scelsi D et al. Electrochemotherapy as a new therapeutic strategy in advanced Merkel cell carcinoma of head and neck region. Radiol Oncol. 2013 Oct 8;47(4):366-369.

Caracò C et al. Long-lasting response to electrochemotherapy in melanoma patients with cutaneous metastasis. BMC Cancer. 2013 Dec 1;13(1):564.

Marandola M et al. Electrochemotherapy and heart function: Treatment in a patient with implantable cardioverter defibrillator/pacemaker. World J Anesthesiol 2013 July 27;2(2):14-17.

Curatolo P et al. Electrochemotherapy: a valid treatment for gorlin-goltz syndrome. Dermatovenerol Croat. 2013 Aug;21(2):132-3.

Kähler KC et al. Palliative treatment of skin metastases in dermato-oncology. J Dtsch Dermatol Ges. 2013;11(11):1041-1045.

Manca G et al. Treatment of keloids and hypertrophic scars with bleomycin and electroporation. Plast Reconstr Surg. 2013 Oct;132(4):621e-630e.

Perrone AM et al. Electrochemotherapy can be used as palliative treatment in patients with repeated loco-regional recurrence of squamous vulvar cancer: a preliminary study. Gynecol Oncol. 2013;130(3):550-553. 

Grocott P et al. Malignant wound management in advanced illness: new insights. Curr Opin Support Palliat Care. 2013;7(1):101-105.

Mali B et al. Tumor size and effectiveness of electrochemotherapy. Radiol Oncol. 2013;47(1):32-41.

Kendler M et al. Electrochemotherapy Under Tumescent Local Anesthesia for the Treatment of Cutaneous Metastases. Dermatol Surg. 2013 Jul;39(7):1023-32.

Kyrgias G et al. Hidradenocarcinoma of the temporal area successfully treated with concomitant electrochemotherapy and radiotherapy. Head Neck Oncol. 2013;5(2):14.

Wiater K et al. Effective treatment of recurrent, advanced dermatofibrosarcoma protuberans by electrochemotherapy. Eur J Dermatol. 2013 Apr 1;23(2):260-261.

Testori A et al. Surgical management of melanoma: an EORTC Melanoma Group survey. Ecancermedicalscience. 2013 Mar 28;7:294.

Rastrelli M et al. Melanoma m (zero): diagnosis and therapy. ISRN Dermatol. 2013 Apr 11;2013:616170.

Curatolo P et al. Complete remission of Merkel cell carcinoma treated with electrochemotherapy and etoposide. G Ital Dermatol Venereol. 2013;148(3):310-311.

Cabula C. Neoadjuvant electrochemotherapy of breast cancer: our experience on first case treated in Italy. Updates Surg. 2013 Dec;65(4):325-328.

Gerlini G et al. Dendritic cells recruitment in melanoma metastasis treated by electrochemotherapy. Clin Exp Metastasis. 2013 Jan;30(1):37-45.


Curatolo P et al. Electrochemotherapy in the Treatment of Kaposi Sarcoma Cutaneous Lesions: A Two-Center Prospective Phase II Trial. Ann Surg Oncol. 2012;(1):192-198.

Campana LG et al. Electrochemotherapy for disseminated superficial metastases from malignant melanoma. Br J Surg. 2012;99(6):821-830.

Campana LG et al. The activity and safety of electrochemotherapy in persistent chest wall recurrence from breast cancer after mastectomy: a phase-II study. Breast Cancer Res Treat. 2012;134(3):1169-1178.

Gargiulo M et al. Electrochemotherapy for non-melanoma head and neck cancers: clinical outcomes in 25 patients. Annals of Surgery. 2012;255(6):1158-1164.

Kis E et al. Treatment of Multiple Basaliomas with Bleomycin-based Electrochemotherapy: A Case Series of Three Patients with Gorlin-Goltz Syndrome. Acta Derm Venereol. 2012;92(6):648-651.

Latini A et al. Effective treatment of Kaposi's sarcoma by electrochemotherapy and intravenous bleomycin administration. Dermatol Ther. 2012;25(2):214-218.

Mali B et al. Antitumor effectiveness of electrochemotherapy: A systematic review and meta-analysis. Eur J Surg Oncol. 2013 Jan;39(1):4-16.

Matthiessen LW et al. Electrochemotherapy for large cutaneous recurrence of breast cancer: A phase II clinical trial. Acta Oncol. 2012;51(6):713-721.

Mevio N et al. Electrochemotherapy for the treatment of recurrent head and neck cancers: preliminary results. Tumori. 2012;98(3):308-313.

Mozzillo N et al. Use of neoadjuvant electrochemotherapy to treat a large metastatic lesion of the cheek in a patient with melanoma. J Transl Med. 2012;10:131.

Testori A et al. Utility of electrochemotherapy in melanoma treatment. Curr Opin Oncol. 2012;24(2):155-161.

Testori A et al. Alternatives for the treatment of local advanced disease: electrochemotherapy, limb perfusion, limb infusion, intralesional IL2. What is the role? Dermatol Ther. 2012;25(5):443-451.

Miklavcic D et al. Electrochemotherapy: technological advancements for efficient electroporation-based treatment of internal tumors. Med Biol Eng Comput. 2012;50(12):1213-1225..

Benevento R et al. Electrochemotherapy of cutaneous metastastes from breast cancer in elderly patients: a preliminary report. BMC surg. 2012;12 Suppl 1:S6.

Gerlini G et al. Enhancing anti-melanoma immunity by electrochemotherapy and in vivo dendritic-cell activation. Oncoimmunology. 2012;1(9):1655-1657.

Linnert M et al. Multiple brain metastases - current management and perspectives for treatment with electrochemotherapy. Radiol Oncol. 2012;46(4):271-278.


Curatolo P et al. Infiltrative basal cell carcinoma successfully treated with electrochemotherapy. Dermatol Exp. 2011;13:141-144.

Edhemovic I et al. Electrochemotherapy: a new technological approach in treatment of metastases in the liver. Technol Cancer Res Treat. 2011;10(5):475-485.

Ongaro A et al. Identification of in vitro electropermeabilization equivalent pulse protocols. Technol Cancer Res Treat. 2011 Oct;10(5):465-473.

Hampton T. Electric pulses help with chemotherapy, may open new paths for other agents. JAMA. 2011;305 (6):549-551.

Macripò G et al. Squamous cell carcinoma of the umbilicus: management of an unusual localization. Tumori. 2011;97(2):236-238.

Kis E et al. Electrochemotherapy of cutaneous metastases of melanoma: a case series study and systematic review of the evidence. Dermatol Surg. 2011;37(6):816-824.

Marenco F et al. Effectiveness of electrochemotherapy in treatment of a recurrent squamous cell carcinoma of the scalp. Eur J Dermatol. 2011;21(4):618-619.

Marone U et al. Metastatic eccrine porocarcinoma: report of a case and review of the literature. World J Surg Oncol. 2011;16;9-32.

Matthiessen LW et al. Management of cutaneous metastases using electrochemotherapy. Acta Oncol. 2011;50(5):621-629.

Muñoz Madero V et al. Electrochemotherapy for treatment of skin and soft tissue tumours. Update and definition of its role in multimodal therapy. Clin Transl Oncol. 2011;13(1):18-24.

Quaglino P et al. FoxP3 expression on melanoma cells is related to early visceral spreading in melanoma patients treated by electrochemotherapy. Pigment Cell Melanoma Res. 2011;24(4):734-736.

Reinhold U. Electrochemotherapy for primary skin cancer and skin metastasis related to other malignancies. Anticancer Drugs. 2011;22(8):711-718.

Skarlatos I et al. Electrochemotherapy in cancer patients: first clinical trial in Greece. In Vivo. 2011;25(2):265-274.


Fini M et al. Ablation of bone cells by electroporation. J Bone Joint Surg Br. 2010 Nov;92(11):1614-2160.

Miklavcic D et al. Towards treatment planning and treatment of deep-seated solid tumors by electrochemotherapy. Biomed Eng Online, 2010;23:9-10.

Testori A et al. Electrochemotherapy for cutaneous and subcutaneous tumour lesions: a novel therapeutic approach. Dermatologic Therapy, 2010;23,651–661.

Kaehler KC et al. Electrochemotherapy in symptomatic Melanoma Skin Metastases: intraindividual comparison with conventional surgery. Dermatol Surg, 2010;36:1-3.

Jarm T et al. Antivascular effects of electrochemotherapy: implications in treatment of bleeding metastases. Expert Rev. Anticancer Ther. 2010;10(5),729-746.

Gargiulo M et al. Electrochemotherapy: Actual Considerations and Clinical Experience in Head and Neck Cancers. Annals of Surgery, 2010;251(4):773.

Gualdi G et al. Electrochemotherapy-induced virus disappearance in HHV-8-positive skin nodules of Kaposi sarcoma: first histological and immunohistochemical demonstration of efficacy. J Eur Acad Dermatol Venereol. 2010;24(2):239-241.

Gothelf A et al. Gene electrotransfer to skin; review of existing literature and clinical perspectives. Curr Gene Ther. 2010;10(4):287-299.


Curatolo P et al. Remission of extensive merkel cell carcinoma after electrochemotherapy. Arch Dermatol. 2009;145(4):494-495.

Snoj M et al. Limb sparing treatment of bleeding melanoma recurrence by electrochemotherapy. Tumori. 2009;95(3):398-402.

Campana LG et al. Bleomycin-Based Electrochemotherapy: Clinical Outcome from a Single Institution's Experience with 52 Patients. Ann Surg Oncol. 2009;16(1):191-199.


Curatolo P et al. Successful Treatment of Penile Kaposi's Sarcoma with Electrochemotherapy. Dermatol Surg. 2008;34:1-5.

Fantini F et al. Basal Cell Carcinoma With Squamous Differentiation. Arch Dermatol. 2008;144(9):1186-1188.

Quaglino P et al. Electrochemotherapy with Intravenous Bleomycin in the Local Treatment of Skin Melanoma Metastases. Annals of Surgical Oncology. 2008;15(8):2215-2222.

Colombo GL et al. Cost-effectiveness analysis of electrochemotherapy with the Cliniporator™ vs other methods for the control and treatment of cutaneous and subcutaneous tumors. Therapeutics and Clinical Risk Management, 2008;4(2) 1-8.

Sersa G et al. Electrochemotherapy in treatment of tumours. EJSO. 2008;34:232-240.

Sersa G et al. Electrochemotherapy of tumours. J Vis Exp. 2008;(22).


Larkin JO et al. Electrochemotherapy: aspects of preclinical development and early clinical experience. Ann Surg. 2007;245(3):469-479.


Sersa G. The state of the art of electrochemotherapy before ESOPE study. Advantages and clinical use. Eur J Cancer, 2006;S4:52-59.

Whelan MC et al. Effective treatment of an extensive recurrent breast cancer which was refractory to multimodal therapy by multiple applications of electrochemotherapy. Eur J Cancer. 2006;S4:32-34.

Garbay JR et al. Successful repetitive tratments by electrochemotherapy of multiple unresectable Kaposi sarcoma nodules. Eur J Cancer. 2006;S4:29-31.

Snoi M et al. Long lasting complete response in melanoma treated by electrochemotherapy. Eur J Cancer. 2006;S4:26-28.

Mir LM et al. Standard operating procedures of the electrochemotherapy: Instructions for the use of bleomycin or cisplatin administered either systemically or locally and electric pulses delivered by the CliniporatorTM by means of invasive or non-invasive electrodes. Eur J Cancer. 2006;S4:14-25.

Marty M et al. Electrochemotherapy – an easy, highly effective and safe treatment of cutaneous and subcutaneous metastases. Results of ESOPE (European Standard Operating Procedures of Electrochemotherapy) study. Eur J Cancer. 2006;S4:3-13.


Snoj M et al. Successful sphincter-saving treatment of anorectal malignant melanoma with electrochemotherapy, local excision and adjuvant brachytherapy. Anti-cancer drugs. 2005;16:345-348.


Jaroszeski MJ et al. Toxicity of anticancer agents mediated by electroporation in vitro. Anticancer Drugs. 2008;11:201-208.


Gehl J et al. Enhancement of citotoxicity by electropermeabilization: an improved method for screening drugs. Anticancer Drugs. 1998;9:319-325.


Mir LM et al. Electrochemotherapy, a new antitumour treatment: first clinical trial. C R Acad Sci III. 1991;313:613-618.


Orlowski S et al. Transient electropermeabilization of cells in culture. Increase of the cytotoxicity of anticancer drugs. Biochem Pharmacol. 1988;37:4727-4733.


Information material

if_file-pdf_285666.png References [*]

[*] The booklet "ELECTROCHEMOTHERAPY: a combined treatment" reports all the papers quoted in this page sorted by treated pathology and the most representative guidelines that mention electrochemotherapy.

Last updated 22 November 2018.

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